Endocrine Abstracts

Background: Leptin and both forms of ghrelin (acylated and des-acylated) are peptide hormones involved in appetite control and food intake regulation in humans. It has been thought that circulating ghrelin concentrations are elevated by fasting and suppressed following a meal, whereas leptin concentrations change in the opposite direction. Most studies, however, only examined these changes after a standardized meal and at different points in time.Objecti...